Get our aProximateâ„¢ PTCs to your lab anywhere in the world (24 & 96-well plates) aProximateâ„¢ Assay-ready plates contain freshly isolated primary human proximal tubule cells (PTCs). The plates are…
Read update 12th October, 2022Damage to the glomerular filtration barrier (GFB) results in protein leakage from the plasma into the urine, so called proteinuria, and is associated with loss of kidney function, which…
Read update 11th August, 2022The glomerulus is the part of the kidney involved in the filtration of solutes and waste from the blood. Damage to the glomerulus by diabetes mellitus, hypertension, glomerulonephritis, or…
Read update 13th July, 2022aProximateâ„¢ Assay-ready plates contain freshly isolated primary human proximal tubule cells (PTCs). The plates are provided in an easy to use 24-well Transwell® format. Visit our product page…
Read update 28th April, 2022Retinal diseases have been at the forefront of gene and cell therapy over the last 30 years with conditions such as macular degeneration and Stargardt disease likely to be…
Read update 5th November, 2021What retinal models are available for drug development? Animal models are the most frequently used for investigating safety and efficacy of ophthalmic drugs. However, due to several key physiological differences,…
Read updateWhy develop an RPE model? Retinal pigment epithelium (RPE) cells play a vital role in the retina by forming the outer blood-retinal barrier and maintaining photoreceptor and visual…
Read update 20th April, 2023One the fastest growing approaches to treat cancer is the use of antibody drug conjugates (ADCs). Since the approval of the first antibody drug conjugate in 2000,…
Read update 13th April, 2023When did you start thinking about incorporating flow into static kidney models? I have been working with static kidney models for over 30 years and started to think about…
Read update 21st March, 2023The Eurostars grant of €1.2m will support the partners, led by Gain, and includes Newcells, the Institute for Research in Biomedicine (Lausanne) and the University of Helsinki. Newcells will…
Read update 27th February, 2023Fibrotic diseases, including liver fibrosis, pulmonary fibrosis, and renal fibrosis, are characterized by the excessive deposition of extracellular matrix (ECM) components, leading to the formation of fibrous tissue that…
Read update 9th February, 2023What is the main advantage of having microglia in the neural retina model? First of all, incorporating microglial cells improves physiological relevance of the current iPSC-derived retinal organoid model…
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