News - Page 4
How to reduce drug attrition during drug development?
There are two main causes of drug attrition: safety and efficacy, and in both instances, the common denominator is the inadequacy of current preclinical models to predict outcomes in…
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Dr Kathryn Garner, Head of Kidney Development at NB
As she narrates her story, you have the impression that you have made the journey with her, her words becoming rich images in…
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iPSC-derived Retinal Organoids: an alternative in vitro model for drug discovery
What retinal models are available for drug development? Animal models are the most frequently used for investigating safety and efficacy of ophthalmic drugs. However, due to several key physiological differences,…
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In vitro models for chronic kidney disease (CKD)
Phosphate balance is central to many metabolic pathways, and the kidneys play a key role in the reabsorption and excretion of phosphate to achieve this balance. In CKD, however,…
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Thought Leadership Workshop hosted by NB: Emerging in vitro technologies for gene therapy applications
These include the first oligonucleotide-based therapies (Spinraza, Exondys, Vyondys), in vivo gene therapies (Luxturna and Zolgensma) and the first cell therapies (Kymriah, Yescarta, Tescartus). Such novel therapeutics treat disorders varying…
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Lung epithelium in vitro modelling of SARS-CoV2 infections to aid Covid-19 treatments
Newcells Biotech’s team has developed a state-of-the-art iPSC-derived in vitro model of the human upper airway to accelerate the development of novel treatments against Covid-19 and other respiratory…
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Global scientific expertise built into every NB product & service
At Newcells Biotech, we build our Industry leading scientific expertise and technical excellence into all the products and services we offer to our customers, delivering innovative solutions for drug…
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NB collaborates with Takeda Pharmaceuticals on renal drug safety evaluation study
Newcells Biotech and Takeda Pharmaceutical International Co. have collaborated in a study designed to assess drug safety. The study evaluated a set of 36 known drugs and…
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Successful EU initiative adds a new 3D lung airway model to NB’s portfolio for drug safety testing
Newcells Biotech is collaborating with industry leaders and expert academics in a European-wide interdisciplinary initiative to develop animal-free methods for drug safety evaluations. The initiative (the EU funded
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Our commitment to the 3Rs
There are few topics more controversial than the use of animals in science, despite the enormous contribution animal experimentation continues to make to the development of new medicines and…
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Newcells Biotech secures over £5m for 3D tissue models
Newcastle-based human stem cell model specialists, Newcells Biotech, have secured a total of £5.25m worth of funding to accelerate their growth plans in the international life sciences market.The funding…
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Developing a 3D in vitro proximal tubule model for chronic toxicity studies
The kidney proximal tubule is of key interest in drug discovery. This is due to its primary role in the excretion and reabsorption of xenobiotics, such as drugs and…
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