We will develop a robust and validated disease model from which you can then obtain key insights into the basis of the disease and enable the rapid evaluation of new treatments in vitro.
You will need to provide us with the relevant iPSCs line for our team of experts to generate and validate the retinal organoids or RPE models.
The validation includes: brightfield imaging morphological characterisation and qualitative and quantitative analysis of key markers expression by fluorescent imaging and gene expression. Studies on RPE also include analysis of phagocytosis of photoreceptors, trans-epithelial resistance (TEER) measurements, growth factor secretion and protein expression analysis by flow cytometry.
What study are you looking to carry out on your disease model?
The following studies can be run individually, or you can combine multiple. Select each individually to progress.
What study are you looking to carry out?
The following studies can be run individually, or you can combine multiple. Select each individually to progress.
