Derivation of a System-Independent Ki for P-glycoprotein Mediated Digoxin Transport from System-Dependent IC50 Data

Aqsaa Chaudhry; Git Chung; Adam Lynn; Akshata Yalvigi; Colin Brown; Harma Ellens; Michael O'Connor; Caroline Lee; Joe Bentz

doi:10.1124/dmd.117.075606

Enhancing the immune function of hiPSC-derived retinal organoids.

Enhancing immune function of hiPSC-derived retinal organoids by incorporating microglial cells

Valeria Chichagova, Maria Georgiou, Birthe Dorgau, Madeleine Carter, Git Chung, Evelyne Sernagor, Lyle Armstrong, Majlinda Lako Investigative Ophthalmology & Visual Science. 2020; 61(7)

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Quantification analysis of immunopositive cells in control and RT organoids.

Room temperature shipment does not affect the biological activity of pluripotent stem cell derived retinal organoids

Maria Georgiou et al. PLoS ONE. 2020; 15(6), e0233860.

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Human iPSC differentiation to retinal organoids in response to IGF1 and BMP4 activation is line- & method-dependent

Valeria Chichagova, Gerrit Hilgen, Ali Ghareeb, Maria Georgiou, Madeleine Carter, Evelyne Sernagor, Majlinda Lako, Lyle Armstrong Stem Cells. 2020; 38(2):195-201

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Differentiation of retinal organoids from human pluripotent stem cells

Valeria Chichagova, Birthe Dorgau, Majed Felemban, Maria Georgiou, Lyle Armstrong, Majlinda Lako Current Protocols in Stem Cell Biology. 2019; 50(1):e95

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The importance of incorporating OCT2 plasma membrane expression and membrane potential in IVIVE of metformin renal secretory clearance

Vineet Kumar, Jia Yin, Sarah Billington, Bhagwat Prasad, Colin D A Brown, Joanne Wang, Jashvant D Unadkat Drug Metabolism and Disposition. 2018; 46(10):1441-1445

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Diagrammatic representation of the culture formats for both single and pooled retinal organoids

Human-induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient-dependent efficiency

Stem Cells. 2018; 36(10):1535-1551

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Resources: Scientific publications - Page 3

Enhancing immune function of hiPSC-derived retinal organoids by incorporating microglial cells

Room temperature shipment does not affect the biological activity of pluripotent stem cell derived retinal organoids

Human iPSC differentiation to retinal organoids in response to IGF1 and BMP4 activation is line- & method-dependent

Differentiation of retinal organoids from human pluripotent stem cells

The importance of incorporating OCT2 plasma membrane expression and membrane potential in IVIVE of metformin renal secretory clearance

Human-induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient-dependent efficiency

Using statistical models to identify key variables critical for generation of retinal organoids from iPSC