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Scientific Publications

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Newcells Biotech

Differentiation of retinal organoids from human pluripotent stem cells

Valeria Chichagova, Birthe Dorgau, Majed Felemban, Maria Georgiou, Lyle Armstrong, Majlinda Lako Current Protocols in Stem Cell Biology. 2019; 50(1):e95

Newcells Biotech

The importance of incorporating OCT2 plasma membrane expression and membrane potential in IVIVE of metformin renal secretory clearance

Vineet Kumar, Jia Yin, Sarah Billington, Bhagwat Prasad, Colin D A Brown, Joanne Wang, Jashvant D Unadkat Drug Metabolism and Disposition. 2018; 46(10):1441-1445

Diagrammatic representation of the culture formats for both single and pooled retinal organoids

Human-induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient-dependent efficiency

Stem Cells. 2018; 36(10):1535-1551

Posters

MPS World Summit 2022: in vitro model of podocyte damage

Development of highly-differentiated human primary proximal tubule MPS model

In vitro renal tubular drug transport modelling

Improved in vitro renal tubular drug transport modelling to meet challenges

Fact Sheets

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Press releases

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Scientific eBooks and Protocols

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Q&A with our scientists

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Videos and Webinars

Tropism of AAV Vectors in Photoreceptor-Like Cells of Human iPSC-Derived Retinal Organoids

Human induced pluripotent stem cell (hiPSC)-derived retinal model containing microglial cells

Predictive in vitro primary proximal tubule models for understanding nephrotoxicity in drug development programs

Predictive in vitro primary proximal tubule models for understanding nephrotoxicity in drug development programs

Case Studies

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Quantitative Fibroblast-to-Myofibroblast Transition (FMT) studies

Quantitative FMT assay with high content imaging

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Human Lung Fibroblasts stimulated with TGF-β for 72 hours and immunostained to detect α-SMA, as a measure of extracellular matrix production and deposition.

In vitro evaluation of ocular toxicity and phenotypic rescue

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Newcells Biotech to develop 3D retinal organoids using hiPSC derived skin cells

In vitro selection of the most relevant species to predict human renal toxicity

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A microscope image of a nephron model

Evaluation of glomerular ADC toxicity in podocytes

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Gene therapy viral vector assessment on retinal organoids

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Gene therapy viral vector assessment on RPE cells

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RPE