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Resources

Scientific Publications

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Enhancing the immune function of hiPSC-derived retinal organoids.

Enhancing immune function of hiPSC-derived retinal organoids by incorporating microglial cells

Valeria Chichagova, Maria Georgiou, Birthe Dorgau, Madeleine Carter, Git Chung, Evelyne Sernagor, Lyle Armstrong, Majlinda Lako Investigative Ophthalmology & Visual Science. 2020; 61(7)

Quantification analysis of immunopositive cells in control and RT organoids.

Room temperature shipment does not affect the biological activity of pluripotent stem cell derived retinal organoids

Maria Georgiou et al. PLoS ONE. 2020; 15(6), e0233860.

Human iPSC differentiation to retinal organoids.

Human iPSC differentiation to retinal organoids in response to IGF1 and BMP4 activation is line- & method-dependent

Valeria Chichagova, Gerrit Hilgen, Ali Ghareeb, Maria Georgiou, Madeleine Carter, Evelyne Sernagor, Majlinda Lako, Lyle Armstrong Stem Cells. 2020; 38(2):195-201

Posters

Developing a Comprehensive Biomarker Package for Detecting Drug-Induced Injury in Podocytes

The aProximate™ in vitro renal proximal tubule cell model as a platform to investigate the renal uptake & nephrotoxic liability of Antisense Oligonucleotide drug molecules

A solution for shipping primary human proximal tubule cell monolayers between laboratories

Fact Sheets

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Press releases

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Scientific eBooks and Protocols

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Q&A with our scientists

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Videos and Webinars

A human iPSC-derived model of SARS-CoV-2 infection and pathogenesis in the lung

A human iPSC-derived model of SARS-CoV-2 infection & pathogenesis in the lung

Reducing compound attrition by predicting renal tubular toxicity with in vitro PTEC models

Reducing compound attrition by predicting renal tubular toxicity with in vitro PTEC models

Improved phenotype of human proximal tubule epithelial cells in a 3D microfluidic model

Case Studies

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Quantitative Fibroblast-to-Myofibroblast Transition (FMT) studies

Quantitative FMT assay with high content imaging

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Human Lung Fibroblasts stimulated with TGF-β for 72 hours and immunostained to detect α-SMA, as a measure of extracellular matrix production and deposition.

In vitro evaluation of ocular toxicity and phenotypic rescue

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Newcells Biotech to develop 3D retinal organoids using hiPSC derived skin cells

In vitro selection of the most relevant species to predict human renal toxicity

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A microscope image of a nephron model

Evaluation of glomerular ADC toxicity in podocytes

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Gene therapy viral vector assessment on retinal organoids

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Gene therapy viral vector assessment on RPE cells

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RPE